JARID2 (N) Antibody, Rabbit Polyclonal
Rabbit polyclonal to JARID2.Jumonji/ARID domain-containing protein 2 (JARID2) is a regulator of histone methyltransferasecomplexes that plays an essential role in embryonic development, including heart and liverdevelopment, neural tube fusion process and hematopoiesis. JARID2 acts by modulating histonemethyltransferase activity and promoting the recruient of histone methyltransferase complexes totheir target genes. JARID2 binds to DNA and mediates the recruient of the PRC2 complex to targetgenes in embryonic stem cells, and plays a key role in differentiation of embryonic stem cells andnormal development. JARID2 does not have histone demethylase activity but regulates activity ofvarious histone methyltransferase complexes.
Product Specifications
Product Name Alternative
Anti-JARID2 antibody, anti-Protein Jumonji antibody, anti-Jumonji antibody, anti-ARID domaincontaining protein 2 antibody, anti-JMJ antibody
UniProt
Q92833
Reactivity
Human, Mouse
Immunogen
N-terminal region of human JARID2
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Epigenetics & Chromatin
Dilution
WB:1:500-1:2000
Purity
Affinity purification
Molecular Weight
139
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Solute Carrier Family 7 Member 6 (SLC7A6) Antibody
Solute Carrier Family 7 Member 6 (SLC7A6) Antibody
Solute Carrier Family 7 Member 6 (SLC7A6) Antibody
Solute Carrier Family 7 Member 6 (SLC7A6) Antibody