L-Leucine (Standard)
L-Leucine (Standard) is the analytical standard of L-Leucine. This product is intended for research and analytical applications. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1].
Product Specifications
CAS Number
61-90-5
Product Name Alternative
Leucine (Standard)
UNSPSC
12352211
Target
Endogenous Metabolite; mTOR; Reference Standards
Type
Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others; PI3K/Akt/mTOR
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/l-leucine-standard.html
Purity
99.94
Smiles
N[C@@H](CC(C)C)C(O)=O
Molecular Formula
C6H13NO2
Molecular Weight
131.17
References & Citations
[1]Baoshan Xu, et al. Stimulation of mTORC1 with L-leucine rescues defects associated with Roberts syndrome. PLoS Genet. 2013;9 (10) :e1003857.|[2]Bruckbauer A, et al. Synergistic effects of leucine and resveratrol on insulin sensitivity and fat metabolism in adipocytes and mice. Nutr Metab (Lond) . 2012 Aug 22;9 (1) :77.|[3]Rachdi L, et al. L-leucine alters pancreatic β-cell differentiation and function via the mTor signaling pathway. Diabetes. 2012 Feb;61 (2) :409-17.
Shipping Conditions
Room Temperature
Storage Conditions
4°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards
Available Sizes
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