Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Macrophage-activating lipopeptide 2 (TFA)

Macrophage-activating lipopeptide 2 TFA is an agonist of Toll like receptors TLR-2/TLR-6. Macrophage-activating lipopeptide-2 enhances endothelial nitric oxide synthase (eNOS) phosphorylation and endothelial cell release of NO, thereby improving vasodilation. Macrophage-activating lipopeptide-2 enhances endothelial adhesion of white blood cells and improve perfusion recovery and collateral growth in the hind limbs of hypercholesterolemic Apoe deficient mice undergoing experimental femoral artery ligation (FAL) [1].

Product Specifications

Product Name Alternative

MALP-2 (TFA)

UNSPSC

12352209

Target

NO Synthase; Toll-like Receptor (TLR)

Type

Peptides

Related Pathways

Immunology/Inflammation

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/macrophage-activating-lipopeptide-2-tfa.html

Purity

98.60

Solubility

DMSO : 50 mg/mL (ultrasonic) |H2O : 1.96 mg/mL (ultrasonic; adjust pH to 12 with 1 M NaOH)

Smiles

O=C(N[C@@H](CCCCN)C(N[C@@H](CCC(O)=O)C(N[C@H](C(O)=O)CCCCN)=O)=O)[C@@H](NC([C@H](CO)NC([C@H]([C@@H](C)CC)NC([C@H](CC(N)=O)NC([C@H](CO)NC([C@H](CCC(O)=O)NC([C@H](CC(O)=O)NC([C@H](CC(N)=O)NC([C@H](CC(N)=O)NC(CNC([C@@H](N)CSC[C@H](OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC1=CC=CC=C1.O=C(O)C(F)(F)F.[x]

Molecular Formula

C99H167N19O30S.xC2HF3O2

Molecular Weight

2135.56 (free base)

References & Citations

[1]Troidl K, et al. The Lipopeptide MALP-2 Promotes Collateral Growth. Cells. 2020 Apr 16;9 (4) :997.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Anti-Beta actin Antibody [B4-B2]
M1210-2TR 20 µL

Anti-Beta actin Antibody [B4-B2]

Sign In for Pricing
View Details
Colterol Hydrochloride
TRC-C215850-25MG 25 mg

Colterol Hydrochloride

Sign In for Pricing
View Details
Progesterone Receptor (PR484), 0.2mg/mL
BNUB0484-100 1x 100 µL

Progesterone Receptor (PR484), 0.2mg/mL

Sign In for Pricing
View Details
TNF-alpha (Tumor Necrosis Factor alpha), 0.2mg/mL
BNUB1674-100 1x 100 µL

TNF-alpha (Tumor Necrosis Factor alpha), 0.2mg/mL

Sign In for Pricing
View Details
Frozen Tissue Sections, Aorta
CS640950 5x 5 µm

Frozen Tissue Sections, Aorta

Sign In for Pricing
View Details
Mouse Sox9 activation kit by CRISPRa
GA204040 1 Kit

Mouse Sox9 activation kit by CRISPRa

Sign In for Pricing
View Details