LDHA Antibody
Mouse Monoclonal antibody to LDHA.LDHA catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA is localized primarily in muscle tissue and is part of the lactate dehydrogenase family. Mutations in LDHA have been linked to exertional myoglobinuria. LDH1 is decreased in essential thrombocythemia. LDHA is induced through a non-genomic pathway of estrogen action. Reduction in LDH-A activity results in stimulation of mitochondrial respiration and decrease of mitochondrial membrane potential.
Product Specifications
Product Name Alternative
Reactivity
Human
Immunogen
Clonality
Monoclonal
Clone
PAT1A4AT
Conjugation
Unconjugated
Field of Research
Metabolism Research
Purification
LDHA antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Host or Source
Mouse
Preservative
1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
Isotype
Mouse IgG2b heavy chain and κ light chain
Available Sizes
Frequently Asked Questions
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