Ubiquinone-1
Ubiquinone-1 is an intermediate in the synthesis of Coenzyme Q. Ubiquinone-1 can be reduced by NADPH oxidase, hepatoma cells, Ascorbic acid[2][3][4][5].
Product Specifications
CAS Number
727-81-1
Product Name Alternative
SHP-141
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite; NADPH Oxidase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Ubiquinone-1.html
Concentration
40 mM * 500 μL in Ethanol
Purity
99.0
Solubility
Ethanol : 10 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1C(OC)=C(OC)C(C(C)=C1C/C=C(C)\C)=O
Molecular Formula
C14H18O4
Molecular Weight
250.29
Precautions
H302, H315, H319, H335
References & Citations
[1]Moller IM, et al. Ubiquinone-1 Induces External Deamino-NADH Oxidation in Potato Tuber Mitochondria. Plant Physiol. 1996 Sep;112 (1) :75-78.|[2]R Fato, et al. Steady-state kinetics of the reduction of coenzyme Q analogs by complex I (NADH:ubiquinone oxidoreductase) in bovine heart mitochondria and submitochondrial particles. Biochemistry. 1996 Feb 27;35 (8) :2705-16.|[3]Stocker R, et al. Extracellular reduction of ubiquinone-1 and -10 by human Hep G2 and blood cells. Biochim Biophys Acta. 1993 Aug 20;1158 (1) :15-22.|[4]Murakami M, et al. NADPH oxidase of guinea-pig macrophages catalyses the reduction of ubiquinone-1 under anaerobic conditions. Biochem J. 1986 Jul 15;237 (2) :541-5.|[5]Roginsky VA, et al. Reduction of ubiquinone-1 by ascorbic acid is a catalytic and reversible process controlled by the concentration of molecular oxygen. Redox Rep. 1996 Feb;2 (1) :55-62.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC040003-500 1x 500 µL
CD45RO (UCHL-1), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680979-100 1x 100 µL
Cytokeratin 8/18 (KRT8/803 + KRT18/835), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC881422-100 1x 100 µL
NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (NX2/1422R), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC740470-100 1x 100 µL
CD45 / LCA (2B11), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC942452-500 1x 500 µL
HER-2 / c-erbB-2 / neu / CD340 (ERBB2/2452), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details