Ubiquinone-1
Ubiquinone-1 is an intermediate in the synthesis of Coenzyme Q. Ubiquinone-1 can be reduced by NADPH oxidase, hepatoma cells, Ascorbic acid[2][3][4][5].
Product Specifications
CAS Number
727-81-1
Product Name Alternative
SHP-141
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite; NADPH Oxidase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Ubiquinone-1.html
Concentration
40 mM * 500 μL in Ethanol
Purity
99.0
Solubility
Ethanol : 10 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1C(OC)=C(OC)C(C(C)=C1C/C=C(C)\C)=O
Molecular Formula
C14H18O4
Molecular Weight
250.29
Precautions
H302, H315, H319, H335
References & Citations
[1]Moller IM, et al. Ubiquinone-1 Induces External Deamino-NADH Oxidation in Potato Tuber Mitochondria. Plant Physiol. 1996 Sep;112 (1) :75-78.|[2]R Fato, et al. Steady-state kinetics of the reduction of coenzyme Q analogs by complex I (NADH:ubiquinone oxidoreductase) in bovine heart mitochondria and submitochondrial particles. Biochemistry. 1996 Feb 27;35 (8) :2705-16.|[3]Stocker R, et al. Extracellular reduction of ubiquinone-1 and -10 by human Hep G2 and blood cells. Biochim Biophys Acta. 1993 Aug 20;1158 (1) :15-22.|[4]Murakami M, et al. NADPH oxidase of guinea-pig macrophages catalyses the reduction of ubiquinone-1 under anaerobic conditions. Biochem J. 1986 Jul 15;237 (2) :541-5.|[5]Roginsky VA, et al. Reduction of ubiquinone-1 by ascorbic acid is a catalytic and reversible process controlled by the concentration of molecular oxygen. Redox Rep. 1996 Feb;2 (1) :55-62.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite
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