Ubiquinone-1

Ubiquinone-1 is an intermediate in the synthesis of Coenzyme Q. Ubiquinone-1 can be reduced by NADPH oxidase, hepatoma cells, Ascorbic acid (HY-B0166) [1][2][3][4][5].

Product Specifications

CAS Number

[727-81-1]

Product Name Alternative

SHP-141

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite; NADPH Oxidase

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/Ubiquinone-1.html

Concentration

40 mM * 500 μL in Ethanol

Purity

99.0

Solubility

Ethanol : 10 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C1C(OC)=C(OC)C(C(C)=C1C/C=C(C)\C)=O

Molecular Formula

C14H18O4

Molecular Weight

250.29

Precautions

H302, H315, H319, H335

References & Citations

[1]Moller IM, et al. Ubiquinone-1 Induces External Deamino-NADH Oxidation in Potato Tuber Mitochondria. Plant Physiol. 1996 Sep;112 (1) :75-78.|[2]R Fato, et al. Steady-state kinetics of the reduction of coenzyme Q analogs by complex I (NADH:ubiquinone oxidoreductase) in bovine heart mitochondria and submitochondrial particles. Biochemistry. 1996 Feb 27;35 (8) :2705-16.|[3]Stocker R, et al. Extracellular reduction of ubiquinone-1 and -10 by human Hep G2 and blood cells. Biochim Biophys Acta. 1993 Aug 20;1158 (1) :15-22.|[4]Murakami M, et al. NADPH oxidase of guinea-pig macrophages catalyses the reduction of ubiquinone-1 under anaerobic conditions. Biochem J. 1986 Jul 15;237 (2) :541-5.|[5]Roginsky VA, et al. Reduction of ubiquinone-1 by ascorbic acid is a catalytic and reversible process controlled by the concentration of molecular oxygen. Redox Rep. 1996 Feb;2 (1) :55-62.