HCV-IN-4
HCV-IN-4 is a potent and orally active HCV NS5A inhibitor, shows great potency against GT1a, GT2b, GT3a, GT1a Y93H and GT1a L31V, with EC90s of 3 pM, 0.3 nM, 0.01 nM, 0.5 nM and 0.02 nM, respectively[1].
Product Specifications
CAS Number
2058080-25-2
UNSPSC
12352209
Target
HCV
Type
Peptides
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/hcv-in-4.html
Solubility
10 mM in DMSO
Smiles
FC1=CC(C2=CN=C([C@@H]3CCCN3C([C@H](C(C)C)NC(OC)=O)=O)N2)=CC4=C1C5=CC6=CC(C7=CN=C([C@H]8N(C([C@H](C(C)C)NC(OC)=O)=O)CCC8)N7)=CC=C6N5[C@H](C9=CC=C(CCCO%10)C%10=C9)O4
Molecular Formula
C52H58FN9O8
Molecular Weight
956.07
References & Citations
[1]Yu W, et al. Discovery of Chromane Containing Hepatitis C Virus (HCV) NS5A Inhibitors with Improved Potency against Resistance-Associated Variants. J Med Chem. 2016 Nov 23;59 (22) :10228-10243. Epub 2016 Nov 9.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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