HCV-IN-4
HCV-IN-4 is a potent and orally active HCV NS5A inhibitor, shows great potency against GT1a, GT2b, GT3a, GT1a Y93H and GT1a L31V, with EC90s of 3 pM, 0.3 nM, 0.01 nM, 0.5 nM and 0.02 nM, respectively[1].
Product Specifications
CAS Number
2058080-25-2
UNSPSC
12352209
Target
HCV
Type
Peptides
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/hcv-in-4.html
Solubility
10 mM in DMSO
Smiles
FC1=CC(C2=CN=C([C@@H]3CCCN3C([C@H](C(C)C)NC(OC)=O)=O)N2)=CC4=C1C5=CC6=CC(C7=CN=C([C@H]8N(C([C@H](C(C)C)NC(OC)=O)=O)CCC8)N7)=CC=C6N5[C@H](C9=CC=C(CCCO%10)C%10=C9)O4
Molecular Formula
C52H58FN9O8
Molecular Weight
956.07
References & Citations
[1]Yu W, et al. Discovery of Chromane Containing Hepatitis C Virus (HCV) NS5A Inhibitors with Improved Potency against Resistance-Associated Variants. J Med Chem. 2016 Nov 23;59 (22) :10228-10243. Epub 2016 Nov 9.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
KN422594 1 Kit
kynurenine 3 monooxygenase (KMO) Human Gene Knockout Kit (CRISPR)
Sign In for Pricing
View Details 
