Flumequine
Product Specifications
UNSPSC Description
Flumequine (R-802) is a quinolone antibiotic, and acts as a topoisomerase II inhibitor, with an IC50 of 15 μM (3.92 μg/mL).
Target Antigen
Antibiotic; Bacterial; Topoisomerase
Type
Reference compound
Related Pathways
Anti-infection;Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection; Cancer
Assay Protocol
https://www.medchemexpress.com/flumequine.html
Purity
99.89
Solubility
DMSO : 7.69 mg/mL (ultrasonic)
Smiles
O=C(C1=CN2C(C)CCC3=C2C(C1=O)=CC(F)=C3)O
Molecular Weight
261.25
References & Citations
[1]Kashida Y, et al. Mechanistic study on flumequine hepatocarcinogenicity focusing on DNA damage in mice. Toxicol Sci. 2002 Oct;69(2):317-21.|[2]Aller-Morán LM, et al. Evaluation of the in vitro activity of flumequine against field isolates of Brachyspira hyodysenteriae. Res Vet Sci. 2015 Dec;103:51-3.|[3]Giraud E, et al. Mechanisms of quinolone resistance and clonal relationship among Aeromonas salmonicida strains isolated from reared fish with furunculosis. J Med Microbiol. 2004 Sep;53(Pt 9):895-901.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-B0526/Flumequine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-B0526/Flumequine-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
42835-25-6
Available Sizes
Curated Selection
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