Guanylin (human)

Guanylin (human), a 15-amino acid peptide, is an endogenous intestinal guanylate cyclase activator. Guanylin (human) is mainly found in gastrointestinal tract which regulates electrolytead water transport in intestinal and renal epithelia through cyclic GMP-dependent mechanism[1][2].

Product Specifications

CAS Number

[183200-12-6]

UNSPSC

12352209

Target

Endogenous Metabolite; Guanylate Cyclase

Type

Peptides

Related Pathways

GPCR/G Protein; Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer; Endocrinology

Assay Protocol

https://www.medchemexpress.com/guanylin-human.html

Purity

99.77

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

[PGTCEICAYAACTGC(Disulfidebridge:Cys4-Cys12;Cys7-Cys15)]

Molecular Formula

C58H87N15O21S4

Molecular Weight

1458.66

References & Citations

[1]M G Currie, et al. Guanylin: an endogenous activator of intestinal guanylate cyclase. Proc Natl Acad Sci U S A. 1992 Feb 1;89 (3) :947-51.|[2]J Bełtowski. Guanylin and related peptides. J Physiol Pharmacol. 2001 Sep;52 (3) :351-75.