Laccase-IN-3
Product Specifications
UNSPSC Description
Laccase-IN-3 (Compound 2b) is a laccase inhibitor (IC50 = 1.02= μM) with significant antifungal activity. Laccase-IN-3 shows superior inhibitory effect on Botryosphaeria dothidea (EC50 = 0.17 mg/L). Laccase-IN-3 effectively blocks the catalytic function of laccase by binding to its active center. Laccase-IN-3 also disrupts pathogen cell membrane integrity and increases ROS[1].
Target Antigen
Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/laccase-in-3.html
Solubility
10 mM in DMSO
Smiles
O=C([C@H]1[C@H](C2)C=C[C@H]2C1)NNC3=CC=C(F)C=C3
Molecular Weight
246.28
References & Citations
[1]Jin DJ, et al. Design, synthesis, antifungal evaluation and mechanism study of novel norbornene derivatives as potential laccase inhibitors. Pest Manag Sci. 2024 Apr 16.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-162488/Laccase-IN-3-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-162488/
Clinical Information
No Development Reported
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