2-Keto-D-Glucose

2-Keto-D-Glucose (D-Glucosone) is a key intermediate in a secondary metabolic pathway leading to the antibiotic Cortalcerone. 2-Keto-D-Glucose is also an intermediate in the conversion of D-glucose into D-fructose. 2-Keto-D-Glucose is found in various natural sources, including fungi, algae, and shellfish[1][2].

Product Specifications

CAS Number

[1854-25-7]

Product Name Alternative

D-Glucosone; D-Arabino-hexos-2-ulose

UNSPSC

12352211

Hazard Statement

H302, H315, H319

Target

Drug Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/2-keto-d-glucose.html

Purity

98.41

Solubility

H2O : 0.2 mg/mL (ultrasonic; warming)

Smiles

OC[C@H]([C@H]([C@@H](C(C=O)=O)O)O)O

Molecular Formula

C6H10O6

Molecular Weight

178.14

Precautions

H302, H315, H319

References & Citations

[1]Sun, Lianhong, et al. Engineering galactose oxidase to increase expression level in E. coli, enhance thermostability, and introduce novel activities. Dissertation (Ph.D.), California Institute of Technology.|[2]zawa K, et al. A novel pyrroloquinoline quinone-dependent 2-keto-D-glucose dehydrogenase from Pseudomonas aureofaciens. J Bacteriol. 2015 Apr;197 (8) :1322-9.|[3]Te-ning E.Liu, et al. Convenient, laboratory procedure for producing solid d-arabino-hexos-2-ulose (d-glucosone) . Carbohydrate Research. Volume 113, Issue 1, 16 February 1983, Pages 151-157.