Racemomycin B
Racemomycin B (229-B; Streptothricin D), the main component from Streptomyces lavendulae OP-2, is a streptothricin antibiotic containing three β-lysine groups. RM-B exhibits antimicrobial activity against plant pathogenic microorganisms and effectively inhibits the growth of Brassica rapa L. roots at 50 ppm. RM-B showed a minimum inhibitory concentration (MIC) of 0.4 μg/ml against Pseudomonas syringae pv. tabaci IFO-3508 and a MIC range of 0.1-2.0 μg/ml against six strains of Fusarium oxysporum, showing stronger antimicrobial activity than RM-A and RM-C. The biological activity of racemomycin compounds increases with the increase in the number of β-lysine groups.
Product Specifications
CAS Number
[3776-37-2]
Product Name Alternative
229-B; Streptothricin D
UNSPSC
12352005
Target
Bacterial
Type
Natural Products
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/racemomycin-b.html
Smiles
O=C(NC[C@H]1O)[C@]2([H])[C@]1([H])NC(N[C@H]3[C@@H]([C@@H]([C@@H](OC(N)=O)[C@@H](CO)O3)O)NC(C[C@@H](N)CCCNC(C[C@@H](N)CCCNC(C[C@@H](N)CCCN)=O)=O)=O)=N2
Molecular Formula
C31H58N12O10
Molecular Weight
758.87
References & Citations
[1]Biological Activities of Racemomycin-B, B-Lysine Rich Streptothricin Antibiotic, the Main Component
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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