Cerlapirdine

Cerlapirdine (SAM-531, PF-05212365) is a selective and potent full antagonist of the 5-hydroxytryptamine 6 (5-HT6) receptor. Cerlapirdine has the potential for researching the Alzheimer's disease[1].

Product Specifications

CAS Number

[925448-93-7]

Product Name Alternative

SAM-531; PF-05212365

UNSPSC

12352005

Target

5-HT Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/cerlapirdine.html

Purity

98.84

Solubility

DMSO : 41.67 mg/mL (ultrasonic; warming; adjust pH to 3 with HCl; heat to 60°C)

Smiles

O=S(C1=NNC2=C1C=C(OCCCN(C)C)C=C2)(C3=C4C=CC=CC4=CC=C3)=O

Molecular Formula

C22H23N3O3S

Molecular Weight

409.50

References & Citations

[1]Tse S, et al. Disposition and metabolic profiling of [ (14) C]cerlapirdine using accelerator mass spectrometry. Drug Metab Dispos. 2014;42 (12) :2023-2032.