GSTP1-1 inhibitor 2
GSTP1-1 inhibitor 2 (Compound 5g) is an hGSTP1-1 (glutathione S-transferase P1-1) inhibitor with an IC50 value of 12.2 μM. GSTP1-1 inhibitor 2 exhibits significant cytotoxicity against DU-145, PC3, and MCF-7 cell lines, with CC50 values of 36.6 μM, 11.9 μM, and 17.4 μM, respectively. It can be used in cancer research[1].
Product Specifications
UNSPSC
12352005
Target
Glutathione S-transferase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/gstp1-1-inhibitor-2.html
Smiles
O=S(C1=CC(C=CC2=O)=C(O2)C=C1)(NC3=CC=C(C(/C=C/C4=CC=C(Cl)C=C4)=O)C=C3)=O
Molecular Formula
C24H16ClNO5S
Molecular Weight
465.91
References & Citations
[1]Sabt A, et al. Novel coumarin-6-sulfonamide-chalcone hybrids as glutathione transferase P1-1 inhibitors. PLoS One. 2024 Aug 14;19 (8) :e0306124.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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