Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

SHP2-IN-29

SHP2-IN-29 (Compound 3) is a potent SHP2 inhibitor with an IC50 value of 0.18 μM. SHP2-IN-29 also has inhibitory activity against PTP1B and TCPTP, with IC50 values of 4.27 and 4.74 μM, respectively.

Product Specifications

CAS Number

2130080-86-1

UNSPSC

12352005

Target

Phosphatase; SHP2

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease; Protein Tyrosine Kinase/RTK

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Cancer; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/shp2-in-29.html

Solubility

10 mM in DMSO

Smiles

O=C(O)C1=C(CC/C=C/C=C/CCC)C=C(O)C=C1O

Molecular Formula

C16H20O4

Molecular Weight

276.33

References & Citations

[1]Sun W, et al. Varic acid analogues from fungus as PTP1B inhibitors: Biological evaluation and structure-activity relationships. Bioorg Med Chem Lett. 2017 Aug 1;27 (15) :3382-3385.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

MTP18 (MTFP1) (NM_001003704) Human Over-expression Lysate
LY423990 100 µg

MTP18 (MTFP1) (NM_001003704) Human Over-expression Lysate

Sign In for Pricing
View Details
Proteinase Activated Receptor 4 (F2RL3) (NM_003950) Human Over-expression Lysate
LY401297 100 µg

Proteinase Activated Receptor 4 (F2RL3) (NM_003950) Human Over-expression Lysate

Sign In for Pricing
View Details
6α-Spiro[androsta-1,4-diene-6,2'-oxiran]-3,17-dione
TRC-S682965-5MG 5 mg

6α-Spiro[androsta-1,4-diene-6,2'-oxiran]-3,17-dione

Sign In for Pricing
View Details
NKIRAS1 (NM_020345) Human Recombinant Protein
TP304248L 1 mg

NKIRAS1 (NM_020345) Human Recombinant Protein

Sign In for Pricing
View Details
(E)-3-Chloro-4-hydroxycinnamic Acid
TRC-C585915-500MG 500 mg

(E)-3-Chloro-4-hydroxycinnamic Acid

Sign In for Pricing
View Details
Munc18 1 (STXBP1) (NM_003165) Human Over-expression Lysate
LY418854 100 µg

Munc18 1 (STXBP1) (NM_003165) Human Over-expression Lysate

Sign In for Pricing
View Details