Proteasome α3 rabbit pAb
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Synonyms
Proteasome subunit alpha type-3 (EC 3.4.25.1;Macropain subunit C8;Multicatalytic endopeptidase complex subunit C8;Proteasome component C8)
Gene ID
5684
UniProt
P25788
Cellular Locus
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human Proteasome α3 AA range: 190-270
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC
Validated Applications
WB,IHC
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000; IHC-p 1:50-300
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES20222-1.pdf
Subcellular Location
Other Product Names
Proteasome subunit alpha type-3 (EC 3.4.25.1; Macropain subunit C8; Multicatalytic endopeptidase complex subunit C8; Proteasome component C8)
Gene ID (Human)
5684
SwissProt (Human)
P25788
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GABA A Receptor alpha 1 (GABRA1) (NM_000806) Human Over-expression Lysate
BTBD6 Antibody - middle region: Biotin (ARP34647_P050-Biotin)