Cytostatin (sodium)
Cytostatin sodium is an effective and selective protein phosphatase 2A (PP2A) inhibitor with an IC50 value of 210 nM. Cytostatin sodium exhibits anti-metastatic properties, good antitumor activity, and can induce apoptosis. Cytostatin sodium can also prevent the adhesion of B16 melanoma cells to components of the extracellular matrix (laminin and collagen) . Cytostatin sodium belongs to the family of natural product fosriecin[1][2][3][4].
Product Specifications
CAS Number
457070-06-3
UNSPSC
12352005
Target
Apoptosis; Phosphatase
Type
Reference compound
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cytostatin-sodium.html
Solubility
10 mM in DMSO
Smiles
O=C1C=C[C@H](C)[C@H]([C@@H](C)CC[C@H](OP(O)(O[Na])=O)[C@@H](C)[C@@H](O)/C=C\C=C/C=C/C)O1
Molecular Formula
C21H32NaO7P
Molecular Weight
450.44
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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