P1,P5-Di (adenosine-5′)-pentaphosphate ammonium salt

P1,P5-di(adenosine-5′)-pentaphosphate ammonium salt is a potent inhibitor of heat shock protein 78 in Leishmania donovani (LdHSP78). LdHSP78 is a putative ClpB protease, that is important for parasite infection of host macrophages and a potential therapeutic target. Enrichment of LdHSP78 in infected humans, hamsters and parasite amastigotes suggested its importance for disease persistence.