Deoxyenterocin
Deoxyenterocin is a bacterial metabolite originally isolated from Streptomyces that has diverse biological activities, including antibiotic, antiviral, and antioxidant properties. It inhibits the growth of S. lutea, S. aureus, K. pneumoniae, and V. percolans in vitro when used at a concentration of 500 μg/mL. Deoxyenterocin (50 μg/mL) inhibits the cytopathic effect of influenza A H1N1 virus by 60.6% in vitro. It also prevents hydrogen peroxide-induced decreases in glutathione (GSH) levels and in the mitochondrial membrane potential in mouse primary cortical neuronal cultures when used at a concentration of 1 μM.
Product Specifications
CAS Number
[108605-51-2]
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/deoxyenterocin.html
Smiles
O=C1[C@]2([C@@](O)(C[C@@]([H])(O1)C3)[C@H]([C@@]3([C@@H]2C(C4=CC=CC=C4)=O)O)C(O5)=CC(OC)=CC5=O)O
Molecular Formula
C22H20O9
Molecular Weight
428.39
References & Citations
[1]Yaginuma, et al. Novel antibiotic 5-deoxyenterocin production by Streptomyces species and its antimicrobiol activities. (1987) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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