MDL27324

MDL27324 is an inhibitor of neutrophil proteases. MDL27324 can be taken up by the cell and has a modest inhibitory effect on the proteolysis of ingested fluoresceinated immune complexes (200 μM, 20% inhibition) [1].

Product Specifications

CAS Number

[123285-50-7]

UNSPSC

12352005

Target

Elastase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/mdl27324.html

Smiles

O=C(N[C@@H](C(C)C)C(C(F)(F)F)=O)[C@H]1N(C([C@H](C)NC([C@H](C)NS(=O)(C2=C3C=CC=C(N(C)C)C3=CC=C2)=O)=O)=O)CCC1

Molecular Formula

C29H38F3N5O6S

Molecular Weight

641.70

References & Citations

[1]N S Doherty, et al. Novel inhibitors of polymorphonuclear neutrophil (PMN) elastase and cathepsin G: evaluation in vitro of their potential for the treatment of inflammatory connective tissue damage. Int J Immunopharmacol. 1990;12 (7) :787-95.