MDL27324
MDL27324 is an inhibitor of neutrophil proteases. MDL27324 can be taken up by the cell and has a modest inhibitory effect on the proteolysis of ingested fluoresceinated immune complexes (200 μM, 20% inhibition) [1].
Product Specifications
CAS Number
123285-50-7
UNSPSC
12352005
Target
Elastase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/mdl27324.html
Smiles
O=C(N[C@@H](C(C)C)C(C(F)(F)F)=O)[C@H]1N(C([C@H](C)NC([C@H](C)NS(=O)(C2=C3C=CC=C(N(C)C)C3=CC=C2)=O)=O)=O)CCC1
Molecular Formula
C29H38F3N5O6S
Molecular Weight
641.70
References & Citations
[1]N S Doherty, et al. Novel inhibitors of polymorphonuclear neutrophil (PMN) elastase and cathepsin G: evaluation in vitro of their potential for the treatment of inflammatory connective tissue damage. Int J Immunopharmacol. 1990;12 (7) :787-95.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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