Human Interferon-gamma (Highly Pure)

<strong>Human Interferon-gamma (Highly Pure)</strong>_x000D_ <strong>Catalog number:</strong> B2010284_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Volume/Weight:</strong> 10 ug_x000D_ <strong>pH:</strong> 7.4 upon reconstitution_x000D_ <strong>Supplied as:</strong> Lyophilized Powder_x000D_ <strong>Appearance:</strong> Powder_x000D_ <strong>Applications:</strong> highly pure Human Interferon-gamma (Highly Pure) expressed in CHO cells. This protein acts as a cytokine with potent immunomodulatory, antiviral and antitumor activities._x000D_ <strong>Storage:</strong> -20C_x000D_ <strong>Keywords:</strong> rHuIFN-γ; IFNG; IFN-gamma; Interferon gamma_x000D_ <strong>Grade:</strong> Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Castro F, Cardoso AP, Gonçalves RM, Serre K, Oliveira MJ. Interferon-Gamma at_x000D_ the Crossroads of Tumor Immune Surveillance or Evasion. Front Immunol. 2018 May_x000D_ 4;9:847._x000D_ _x000D_ 2: Alspach E, Lussier DM, Schreiber RD. Interferon γ and Its Important Roles in_x000D_ Promoting and Inhibiting Spontaneous and Therapeutic Cancer Immunity. Cold_x000D_ Spring Harb Perspect Biol. 2019 Mar 1;11(3):a028480._x000D_ _x000D_ 3: Schroder K, Hertzog PJ, Ravasi T, Hume DA. Interferon-gamma: an overview of_x000D_ signals, mechanisms and functions. J Leukoc Biol. 2004 Feb;75(2):163-89._x000D_ _x000D_ 4: Carinelli S, Xufré C, Martí M, Pividori MI. Interferon gamma transcript_x000D_ detection on T cells based on magnetic actuation and multiplex double-tagging_x000D_ electrochemical genosensing. Biosens Bioelectron. 2018 Oct 15;117:183-190._x000D_ _x000D_ 5: Razaghi A, Owens L, Heimann K. Review of the recombinant human interferon_x000D_ gamma as an immunotherapeutic: Impacts of production platforms and_x000D_ glycosylation. J Biotechnol. 2016 Dec 20;240:48-60._x000D_ _x000D_ 6: Liu S, Yu X, Wang Q, Liu Z, Xiao Q, Hou P, Hu Y, Hou W, Yang Z, Guo D, Chen_x000D_ S. Specific Expression of Interferon-γ Induced by Synergistic Activation_x000D_ Mediator-Derived Systems Activates Innate Immunity and Inhibits Tumorigenesis. J_x000D_ Microbiol Biotechnol. 2017 Oct 28;27(10):1855-1866._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/30663507/">7: Don ЕS, Bobrovnik SА, Sherriff G, Myslivets AА, Tarasov SА, Epstein ОI._x000D_ Advanced approach to activity evaluation for released-active forms of antibodies_x000D_ to interferon-gamma by enzyme-linked immunoassay. J Immunoassay Immunochem._x000D_ 2019;40(3):250-268. </a>_x000D_ _x000D_ <strong>Products Related to Human Interferon-gamma (Highly Pure) </strong> <a href="https://moleculardepot.com/product-category/Proteins/">: Proteins</a>