NSC 689534

NSC 689534 can form copper chelate with Cu2+. NSC 689534/Cu2+ complex is a potent oxidative stress inducer, and has antitumor activity[1].

Product Specifications

CAS Number

[907958-80-9]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Cuproptosis

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/nsc-689534.html

Purity

96.31

Solubility

10 mM in DMSO

Smiles

S=C(N(CC1=NC=CC=C1)CC2=NC=CC=C2)N/N=C/C3=NC=CC=C3

Molecular Formula

C19H18N6S

Molecular Weight

362.45

Precautions

H302, H315, H319, H335

References & Citations

[1]Chad N Hancock, et al. A copper chelate of thiosemicarbazone NSC 689534 induces oxidative/ER stress and inhibits tumor growth in vitro and in vivo. Free Radic Biol Med. 2011 Jan 1;50 (1) :110-21.|[2]Hancock CN, et al. A copper chelate of thiosemicarbazone NSC 689534 induces oxidative/ER stress and inhibits tumor growth in vitro and in vivo. Free Radic Biol Med. 2011 Jan 1;50 (1) :110-21.