NSC 689534
NSC 689534 can form copper chelate with Cu2+. NSC 689534/Cu2+ complex is a potent oxidative stress inducer, and has antitumor activity[1].
Product Specifications
CAS Number
[907958-80-9]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Cuproptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nsc-689534.html
Purity
96.31
Solubility
10 mM in DMSO
Smiles
S=C(N(CC1=NC=CC=C1)CC2=NC=CC=C2)N/N=C/C3=NC=CC=C3
Molecular Formula
C19H18N6S
Molecular Weight
362.45
Precautions
H302, H315, H319, H335
References & Citations
[1]Chad N Hancock, et al. A copper chelate of thiosemicarbazone NSC 689534 induces oxidative/ER stress and inhibits tumor growth in vitro and in vivo. Free Radic Biol Med. 2011 Jan 1;50 (1) :110-21.|[2]Hancock CN, et al. A copper chelate of thiosemicarbazone NSC 689534 induces oxidative/ER stress and inhibits tumor growth in vitro and in vivo. Free Radic Biol Med. 2011 Jan 1;50 (1) :110-21.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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