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Ebselen

Product Specifications

Background

Glutathione peroxidase mimetic [1, 4]. Peroxynitrite scavenger [4]. Anti-inflammatory [1, 5-7] Antioxidant [2, 3, 5]. Protein kinase C (PKC), NADPH, lipoxygenase, COX, NOS, H+-ATPase and NADPH oxidase inhibitor [6-9]. Antifungal [9]. Review [10]. Potent IDO-1 inhibitor with Ki 94nM [11]. Inhibitor of HIV-1 capsid C-terminal domain dimerization. Shown to potentially inhibit the 33.8-kDa Main Protease (Mpro) /3C-like Protease of SARS-CoV-2, consequently inhibiting viral transcription and replication and possibly inhibiting spread of COVID-19

CAS Number

60940-34-3

Type

Chemical

Purity

Greater than or equal to 98% (HPLC)

Shipping Conditions

Room Temp

Storage Conditions

Short Term Storage:+4C. Long Term Storage: -20C. Handling Advice: Protect from light. Use/Stability: Stable for at least 2 years after receipt when stored at -20C.

Calculated Molecular Weight

274.2

Other Product Names

2-Phenyl-1,2-benzisoselenazol-3- (2H) -one

Physical Properties

Lyophilized

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