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Six Transmembrane Epithelial Antigen of Prostate Detection Set

Product Specifications

Background

For images please see PDF data sheet

CAS Number

9007-83-4

Reactivity

Human

Immunogen

Rabbit polyclonal antibodies were raised against peptides corresponding to amino acid sequences from each of the corresponding proteins.

Clonality

Polyclonal

Type

Detection Sets

Purification

Antibodies are supplied as affinity chromatography purified IgG.

Concentration

Antibody 1 mg/mL

Buffer

PBS containing 0.02% sodium azide.

Shipping Conditions

Blue Ice

Storage Conditions

Stable at 4˚ C for three months, store at -20˚ C for up to one year.

Applications Notes

These polyclonal antibodies can be used for detection of STEAP1 - 4 by immunoblot at 1 - 2 μ g/mL, and for detection of STEAP1 - 3 by immunohistochemistry at 2.5 - 5 μ g/mL, and Immunoflourescence.

Background Reference 01

Hubert RS, Vivanco I, Chen E, et al. STEAP: a prostate-specific cell-surface antigen highly expressed in human prostate tumors. Proc. Natl. Acad. Sci. USA 1999; 96:14523-8.

Background Reference 02

Ohgami RS, Campagna DR, McDonald A, et al. The Steap proteins are metalloreductases. Blood 2006; 108:1388-94.

Background Reference 03

Ohgami RS, Campagna DR, Greer EL, et al. Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Nat. Genet. 2005; 37:1264-9.

Background Reference 04

Alves PM, Faure O, Graff-Dubois S, et al. STEAP, a prostate tumor antigen, is a target of human CD8+ T cells. Cancer Immunol. Immunother. 2006; 55:1515-23.

Tested Applications

WB, IHC, IF

Physical Properties

Liquid

Frequently Asked Questions

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