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TRAIL and Receptor Detection Set

Product Specifications

Background

For images please see PDF data sheet

Reactivity

Human

Immunogen

Rabbit polyclonal antibodies were raised against peptides corresponding to amino acid sequences from each of the corresponding proteins.

Clonality

Polyclonal

Type

Detection Sets

Purification

Antibodies are supplied as affinity chromatography purified IgG.

Concentration

Antibody 1 mg/mL

Buffer

PBS containing 0.02% sodium azide.

Shipping Conditions

Blue Ice

Storage Conditions

Stable at 4˚ C for three months, store at -20˚ C for up to one year.

Background Reference 01

Wiley SR, Schooley K, Smolak PJ, et al. Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity 1995; 3:673-82.

Background Reference 02

Pitti RM, Marsters SA, Ruppert S, et al. Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family. J. Biol. Chem. 1996; 271:12687-90.

Background Reference 03

Schneider P, Thome M, Burns K, et al. TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-κ B. Immunity 1997; 7:831-6.

Background Reference 04

Pan G, O’Rourke K, Chinnaiyan AM, et al. The receptor for the cytotoxic ligand TRAIL. Science 1997; 276:111-3.

Tested Applications

WB, IHC, IF

Physical Properties

Liquid

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