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Tubulin inhibitor 48

Tubulin inhibitor 48 (compound 16) is an anti-cancer agent targeting tubulin. Tubulin inhibitor 48 has an IC50 of 0.1 and 0.07 μM for LN-229 and Capan-1 cell, respectively[1].

Product Specifications

CAS Number

63589-51-5

UNSPSC

12352005

Target

Microtubule/Tubulin

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tubulin-inhibitor-48.html

Smiles

CN1C(C(C2=N)=CC3=C(O2)C=C(N(CC)CC)C=C3)=NC4=CC=CC=C14

Molecular Formula

C21H22N4O

Molecular Weight

346.43

References & Citations

[1]Ida Boček Pavlinac, et al. Synthesis of novel imino-coumarin and acrylonitrile 2-benzazole hybrids as potent anticancer agents targeting tubulin. Bioorg Chem. 2024 Nov 22:154:107991.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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