SMURF1 Peptide
Product Specifications
NCBI Gene ID
57154
Type
Peptides
Concentration
200 ug/mL
Buffer
PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
Shipping Conditions
Blue Ice
Storage Conditions
Store SMURF1 peptide at -20˚ C, stable for one year.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=7945P
Applications Notes
SMURF1 peptide is used for blocking the activity of SMURF1 antibody.
NCBI Official Name
SMAD specific E3 ubiquitin protein ligase 1
NCBI Organism
Homo sapiens
Background Reference 01
Huibregtse JM, Scheffner M, Beaudenon S, et al. A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase. Proc. Natl. Acad. Sci. USA 1995; 92:2563-7.
Background Reference 02
Hwang YS, Lee HS, Kamata T, et al. The Smurf ubiquitin ligases regulate tissue separation via antagonistic interactions with ephrinB1. Genes Dev. 2013; 27:491-503.
Background Reference 03
Yamashita M, Ying SX, Zhang G, et al. Ubiquitin ligase Smurf1 controls osteoblast activity and bone homeostasis by targeting MEKK2 for degradation. Cell 2005; 121:101-113.
Background Reference 04
Kwon A, Lee HL, Woo KM, et al. SMURF1 plays a role in EGF-induced breast cancer cell migration and invasion. Mol. Cells 2013; 36:548-55.
Tested Applications
Blocking
Species
Human
Physical Properties
Liquid
Curated Selection
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