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NOX2 Peptide

Product Specifications

NCBI Gene ID

1536

Swiss Prot

P04839

Accession Number

NP_000388

Type

Peptides

Concentration

200 ug/mL

Buffer

PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide

Shipping Conditions

Blue Ice

Storage Conditions

Store NOX2 Peptide at -20˚ C, stable for one year.

Applications Notes

The peptide is used for blocking the activity of NOX2 Antibody (catalog number 7923) . It usually blocks the antibody activity completely by incubating the peptide with equal volume of antibody for 30 min at 37˚ C.

NCBI Official Name

Cytochrome b-245, beta polypeptide

NCBI Organism

Homo sapiens

Background Reference 01

Bedard K and Krause KH. The Nox family of ROS-generating NAPDH oxidases: physiology and pathophysiology. Physiol. Rev. 2007; 87:245-313.

Background Reference 02

Segal AW. Cytochrome b-245 and its involvement in the molecular pathology of chronic granulomatous disease. Hematol. Oncol. North Am. 1988; 2:213-23.

Background Reference 03

Surace MJ and Block ML. Targeting microglia-mediated neurotoxicity: the potential of NOX2 inhibitors. Cell Mol. Life Sci. 2012; 69:2409-27.

Other Product Names

CGD, NOX2, AMCBX2, GP91-1, GP91PHOX, p91-PHOX, GP91-PHOX, Cytochrome b-245 heavy chain, CGD91-phox, Cytochrome b558 subunit beta

Tested Applications

Blocking

Species

Human

Protein ID

6996021

Physical Properties

Liquid

Frequently Asked Questions

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