NOX1 Peptide

Product Specifications

NCBI Gene ID

27035

Swiss Prot

Q9Y5S8

Accession Number

NP_008983

Type

Peptides

Concentration

200 ug/mL

Buffer

PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide

Shipping Conditions

Blue Ice

Storage Conditions

Store NOX1 Peptide at -20˚ C, stable for one year.

Applications Notes

The peptide is used for blocking the activity of NOX1 Antibody (catalog number 7921) . It usually blocks the antibody activity completely by incubating the peptide with equal volume of antibody for 30 min at 37˚ C.

NCBI Official Name

NADPH oxidase 1

NCBI Organism

Homo sapiens

Background Reference 01

Helmcke I, Heumuller S, Tikkanen R, et al. Identification of structural elements in Nox1 and Nox4 controlling localization and activity. Antioxid. Redox Signal. 2009; 11:1279-87.

Background Reference 02

Piccoli C, D'Aprile A, Ripoli M, et al. Bone-marrow derived hematopoietic stem/progenitor cells express multiple isoforms of NADPH oxidase and produce constitutively reactive oxygen species. Biochem. Biophys. Res. Commun. 2007; 353:965-72.

Background Reference 03

Lee JG, Lim EJ, Park DW, et al. A combination of Lox-1 and Nox1 regulates TLR9-mediated foam cell formation. Cell Signal. 2008; 20:2266-75.

Background Reference 04

Stanic B, Katsuyama M, and Miller FJ Jr. An oxidized extracellular oxidation-reduction state increases Nox1 expression and proliferation in vascular smooth muscle cells via epidermal growth factor receptor activation. Arterioscler. Thromb. Vasc. Biol. 2010; 30:2234-41.