SNCA Peptide

Product Specifications

NCBI Gene ID

6622

Swiss Prot

P37840

Accession Number

NP_000336

Type

Peptides

Concentration

200 ug/mL

Buffer

PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide

Shipping Conditions

Blue Ice

Storage Conditions

Store SNCA Peptide at -20˚ C, stable for one year.

Applications Notes

The peptide is used for blocking the activity of SNCA Antibody (catalog number 7911) . It usually blocks the antibody activity completely by incubating the peptide with equal volume of antibody for 30 min at 37˚ C.

NCBI Official Name

Synuclein, alpha (non A4 component of amyloid precursor)

NCBI Organism

Homo sapiens

Background Reference 01

Ueda K, Fukushima H, Masliah E, et al. Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease. Proc. Natl. Acad. Sci. USA 1993; 90:11282-6.

Background Reference 02

Pronin AN, Morris AJ, Surguchov A, et al. Synucleins are a novel class of substrates for G protein-coupled receptor kinases. J. Biol. Chem. 2000; 275:26515-22.

Background Reference 03

Oaks AW, Frankfurt M, Finkelstein DI, et al. Age-dependent effects of A53T alpha-synuclein on behavior and dopaminergic function. PLoS One 2013; 8:e60378.

Background Reference 04

Polymeropoulos MH, Lavedan C, Leroy E, et al. Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. Science 1997; 276:2045-7.