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PARK2 Peptide

Product Specifications

NCBI Gene ID

5071

Swiss Prot

O60260

Accession Number

NP_004553

Type

Peptides

Concentration

200 ug/mL

Buffer

PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide

Shipping Conditions

Blue Ice

Storage Conditions

Store PARK2 Peptide at -20˚ C, stable for one year.

Applications Notes

The peptide is used for blocking the activity of PARK2 Antibody (catalog number 7903) . It usually blocks the antibody activity completely by incubating the peptide with equal volume of antibody for 30 min at 37˚ C.

NCBI Official Name

Parkin RBR E3 ubiquitin protein ligase

NCBI Organism

Homo sapiens

Background Reference 01

Dauer W and Przedborski S. Parkinson’s disease: Mechanisms and models. Neuron 2003; 39:889-909.

Background Reference 02

Kitada T, Asakawa S, Hattori N, et al. Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 1998; 392:605-8.

Background Reference 03

Shimura H, Hattori N, Kubo Si, et al. Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase. Nat. Genet. 2000; 25:302-5.

Background Reference 04

Johnson BN, Berger AK, Cortese GP, et al. The ubiquitin E3 ligase parkin regulates the proapoptotic function of Bax. Proc. Natl. Acad. Sci. USA 2012; 109:6283-88.

Other Product Names

PDJ, PRKN, AR-JP, LPRS2, E3 ubiquitin-protein ligase parkin, Parkinson juvenile disease protein 2, Parkinson disease protein 2

Tested Applications

Blocking

Species

Human

Protein ID

169790969

Physical Properties

Liquid

Frequently Asked Questions

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