HDAC1 Peptide

Product Specifications

NCBI Gene ID

3065

Swiss Prot

Q13547

Accession Number

NP_004955

Type

Peptides

Concentration

200 ug/mL

Buffer

PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide

Shipping Conditions

Blue Ice

Storage Conditions

Store HDAC1 Peptide at -20˚ C, stable for one year.

Applications Notes

The peptide is used for blocking the activity of HDAC1 Antibody (catalog number 7897) . It usually blocks the antibody activity completely by incubating the peptide with equal volume of antibody for 30 min at 37˚ C.

NCBI Official Name

Histone deacetylase 1

NCBI Organism

Homo sapiens

Background Reference 01

Taunton J, Hassig CA, and Schreiber SL. A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p. Science 1996; 272:408-11.

Background Reference 02

Cai RL, Yan-Neale Y, Cueto MA, et al. HDAC1, a histone deacetylase, forms a complex with Hus1 and Rad9, two G2/M checkpoint Rad proteins. J. Biol. Chem. 2000; 275:27909-16.

Background Reference 03

Winter M, Moser MA, Meunier D, et al. Divergent roles of HDAC1 and HDAC2 in the regulation of epidermal development and tumorigenesis. EMBO J. 2013; 32:3176-91.

Background Reference 04

Turgeon N, Blais M, Gagné JM, et al. HDAC1 and HDAC2 restrain the intestinal inflammatory response by regulating intestinal epithelial cell differentiation. PLoS One 2013; 8:e73785.