IC-1k
IC-1k is a potent HIV-1 inhibitor with EC50 values of 2.69, 97.97 nM for HIV-1 IIIB, HIV-2 ROD, respectively. IC-1k shows cytotoxicity. IC-1k shows antiviral activity[1].
Product Specifications
UNSPSC
12352211
Target
HIV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ic-1k.html
Smiles
FC1=CC(C[C@@H](C(N(C2=CC3=C(SC=N3)C=C2)C)=O)NC(CC4=CNC5=C4C=C(O)C=C5)=O)=CC(F)=C1
Molecular Formula
C27H22F2N4O3S
Molecular Weight
520.55
References & Citations
[1]Xu S, et al. "Pseudosubstrate Envelope"/Free Energy Perturbation-Guided Design and Mechanistic Investigations of Benzothiazole HIV Capsid Modulators with High Ligand Efficiency. J Med Chem. 2024 Oct 17.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HIV-1; HIV-2
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