Triptoquinone B
Triptoquinone B ((+) -Triptoquinone B), a sesquiterpene alkaloid, is an interleukin-1 inhibitor. Triptoquinone B shows potent inhibitory activities against interleukin 1α and β releases for human peripheral mononuclear cells[1][2].
Product Specifications
CAS Number
142937-50-6
Product Name Alternative
(+) -Triptoquinone B
UNSPSC
12352211
Target
Interleukin Related
Type
Natural Products
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/triptoquinone-b.html
Solubility
10 mM in DMSO
Smiles
O=C1C(C(C)C)=CC(C([C@@]2(C)CC3)=C1CC[C@@]2([H])[C@@](C)(CO)C3=O)=O
Molecular Formula
C20H26O4
Molecular Weight
330.42
References & Citations
[1]Takaishi Y, et, al. Triptoquinone A and B novel interleukin-1 inhibitors from Tripterygium wilfordii var Regeli. Tetrahedron Letters. 1992 Nov; 33 (47) : 7177-7180.|[2]Wang XD, et, al. Terpene alkaloids from Tripterygium wilfordii. J Asian Nat Prod Res. 2005 Oct;7 (5) :755-9.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
IL-1
Available Sizes
Frequently Asked Questions
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