Glutathione sulfonate
Glutathione sulfonate (S-Sulfoglutathione) is a multifunctional bioactive compound that inhibits angiogenesis and tumor growth. Glutathione sulfonate is a competitive inhibitor of glutathione S-transferase and is involved in the detoxification process and the binding of a variety of exogenous and endogenous compounds. Glutathione sulfonate acts in the substrate binding site of Escherichia coli glutathione S-transferase, affecting the catalytic mechanism. The structural characteristics of Glutathione sulfonate contribute to its inhibitory effect by hydrogen bonding in the active center of the enzyme[1].
Product Specifications
CAS Number
[1637-70-3]
Product Name Alternative
S-Sulfoglutathione
UNSPSC
12352100
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/glutathione-sulfonate.html
Purity
96.12
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
OC([C@@H](N)CCC(N[C@@H](CSS(=O)(O)=O)C(NCC(O)=O)=O)=O)=O
Molecular Formula
C10H17N3O9S2
Molecular Weight
387.39
References & Citations
[1]Three-dimensional structure of Escherichia coli glutathione S-transferase complexed with glutathione sulfonate: catalytic roles of Cys10 and His106
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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