Theaflavin-3-gallate (Standard)
Theaflavin-3-gallate (Standard) is the analytical standard of Theaflavin-3-gallate. This product is intended for research and analytical applications. Theaflavin-3-gallate, a black tea theaflavin monomer, is regarded as the biologically important active component of black tea and provides health benefits. Theaflavin-3-gallate acts as prooxidants and induces oxidative stress in the carcinoma cells. Theaflavin-3-gallate reacts directly with reduced glutathione (GSH) in a time- and concentration-dependent manner. Theaflavin-3-gallate induces apoptosis and G1 cell cycle arrest in ovarian cancer A2780/CP70 cells through p53-dependent pathways. Theaflavin-3-gallate induces DNA damage through ATM/Chk/p53 pathway[1][2].
Product Specifications
CAS Number
30462-34-1
UNSPSC
12352005
Target
Apoptosis; ATM/ATR; Checkpoint Kinase (Chk) ; MDM-2/p53; Reference Standards
Type
Reference Standards
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Others; PI3K/Akt/mTOR
Field of Research
Cancer
Smiles
O=C(O[C@H]1[C@@H](C(C=C2O)=CC3=C([C@@H]4[C@H](O)CC5=C(O)C=C(O)C=C5O4)C=C(O)C(O)=C3C2=O)OC6=CC(O)=CC(O)=C6C1)C7=CC(O)=C(O)C(O)=C7
Molecular Formula
C36H28O16
Molecular Weight
716.60
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Clinical Information
No Development Reported
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Ep-CAM / CD326 (VU-1D9), CF647 conjugate, 0.1mg/mL
TGF-beta (1D11.16.8), CF405S conjugate, 0.1mg/mL
Major Vault Protein (MVP) (1032), CF647 conjugate, 0.1mg/mL
