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Cys-Gly-Lys-Lys-Gly-Amyloid β-Protein (36-42)

Cys-Gly-Lys-Lys-Gly-Amyloid β-Protein (36-42) is the 36-42 fragment of Amyloid β-Protein. β-amyloid, a polypeptide made up of 36-43 amino acids, is the main component of amyloid plaques found in the brains of people with Alzheimer's disease. β-amyloid oligomers (Aβos) plays A key role in the progression of Alzheimer's disease (AD) by inducing neuronal damage and cognitive impairment[1].

Product Specifications

CAS Number

[1802078-25-6]

UNSPSC

12352209

Target

Amyloid-β

Type

Peptides

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/cys-gly-lys-lys-gly-amyloid-β-protein-36-42.html

Solubility

10 mM in DMSO

Smiles

SC[C@H](N)C(NCC(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(NCC(N[C@@H](C(C)C)C(NCC(NCC(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C47H86N14O13S

Molecular Weight

1087.34

References & Citations

[1]Huang YR, et al. The Toxicity and Polymorphism of β-Amyloid Oligomers. Int J Mol Sci. 2020 Jun 24;21 (12) :4477.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

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