MMV665916
MMV665916, a quinazolinedione derivative, is an antimalarial agent. MMV665916 displays antiplasmodial activity against P. falciparum FcB1 strain with EC50 value of 0.4 μM and presents the high selectivity index (SI>250) [1].
Product Specifications
CAS Number
896356-25-5
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/mmv665916.html
Solubility
10 mM in DMSO
Smiles
O=C1N(CCC(NCC2=CC=CC=C2OC)=O)C(C3=CC=CC=C3N1)=O
Molecular Formula
C19H19N3O4
Molecular Weight
353.37
References & Citations
[1]Laura Mourot, et al. Structure-activity relationship and molecular modelling studies of quinazolinedione derivatives MMV665916 as potential antimalarial agent. Bioorg Med Chem. 2021 Dec 1;51:116513.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Plasmodium
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