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Vericiguat

Vericiguat (BAY1021189) is a potent, orally available and soluble guanylate cyclase stimulator.

Product Specifications

CAS Number

1350653-20-1

Product Name Alternative

BAY1021189

UNSPSC

12352005

Hazard Statement

H302

Target

Guanylate Cyclase

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Cardiovascular Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/Vericiguat.html

Purity

99.27

Solubility

DMSO : 60 mg/mL (ultrasonic)

Smiles

O=C(OC)NC1=C(N)N=C(C2=NN(CC3=CC=CC=C3F)C4=NC=C(F)C=C42)N=C1N

Molecular Formula

C19H16F2N8O2

Molecular Weight

426.38

Precautions

H302

References & Citations

[1]Follmann M, et al. Discovery of the Soluble Guanylate Cyclase Stimulator Vericiguat (BAY 1021189) for the Treatment of Chronic Heart Failure. J Med Chem. 2017 Jun 22;60 (12) :5146-5161.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Launched

Available Sizes

Frequently Asked Questions

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