Vericiguat
Vericiguat (BAY1021189) is a potent, orally available and soluble guanylate cyclase stimulator.
Product Specifications
CAS Number
[1350653-20-1]
Product Name Alternative
BAY1021189
UNSPSC
12352005
Hazard Statement
H302
Target
Guanylate Cyclase
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/Vericiguat.html
Purity
99.27
Solubility
DMSO : 60 mg/mL (ultrasonic)
Smiles
O=C(OC)NC1=C(N)N=C(C2=NN(CC3=CC=CC=C3F)C4=NC=C(F)C=C42)N=C1N
Molecular Formula
C19H16F2N8O2
Molecular Weight
426.38
Precautions
H302
References & Citations
[1]Follmann M, et al. Discovery of the Soluble Guanylate Cyclase Stimulator Vericiguat (BAY 1021189) for the Treatment of Chronic Heart Failure. J Med Chem. 2017 Jun 22;60 (12) :5146-5161.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
Curated Selection
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