ZW10 Interactor Recombinant Protein
Product Specifications
Background
ZW10 Interactor is localized to the kinetochores from late Prophase to Anaphase and has a uniform distribution in the cytoplasm of Interphase cells. ZWINT interacts ZW10, MIS12 and NDC80 subunit of the NDC80 complex specifically during mitosis. ZWINT is a part of the MIS12 complex which is required for kinetochore formation and spindle checkpoint activity. In addition, ZWINT is required to target ZW10 to the kinetochore at prometaphase.
CAS Number
9000-83-3
NCBI Gene ID
11130
Swiss Prot
O95229
Accession Number
O95229
Tag
N-6 His tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Cell Cycle
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
33.4 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
ZW10 interacting kinetochore protein
NCBI Organism
Homo sapiens
Other Product Names
ZW10 Interactor, ZW10-Interacting Protein 1, Zwint-1, ZWINT
Species
Human
Physical Properties
Lyophilized
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