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ZW10 Interactor Recombinant Protein

Product Specifications

Background

ZW10 Interactor is localized to the kinetochores from late Prophase to Anaphase and has a uniform distribution in the cytoplasm of Interphase cells. ZWINT interacts ZW10, MIS12 and NDC80 subunit of the NDC80 complex specifically during mitosis. ZWINT is a part of the MIS12 complex which is required for kinetochore formation and spindle checkpoint activity. In addition, ZWINT is required to target ZW10 to the kinetochore at prometaphase.

CAS Number

9000-83-3

NCBI Gene ID

11130

Swiss Prot

O95229

Accession Number

O95229

Tag

N-6 His tag

Type

Recombinant Proteins

Source

E. coli

Field of Research

Cell Cycle

Buffer

Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

Shipping Conditions

Room Temp

Calculated Molecular Weight

33.4 kD

Applications Notes

This recombinant protein can be used for biological assays. For research use only.

NCBI Official Name

ZW10 interacting kinetochore protein

NCBI Organism

Homo sapiens

Other Product Names

ZW10 Interactor, ZW10-Interacting Protein 1, Zwint-1, ZWINT

Species

Human

Physical Properties

Lyophilized

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