Uroplakin-2 Recombinant Protein
Product Specifications
Background
Uroplakin-2 is a single-pass type I membrane protein that belongs to the uroplakin-2 family. Uroplakin-2 is a component of the asymmetric unit membrane (AUM) and expressed in the ureter, a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. Uroplakin-2 forms heterodimer with UPK1A that is necessary for exiting out of the endoplasmic reticulum (ER) . Uroplakin-2 may play an important role in regulating the assembly of the AUM. AUM is believed to strengthen the urothelium by preventing cell rupture during bladder distention.
CAS Number
9000-83-3
NCBI Gene ID
7379
Swiss Prot
O00526
Accession Number
O00526
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
14.84 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Uroplakin 2
NCBI Organism
Homo sapiens
Other Product Names
Uroplakin-2, UP2, Uroplakin II, UPII, UPK2
Species
Human
Physical Properties
Lyophilized
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