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Uroplakin-2 Recombinant Protein

Product Specifications

Background

Uroplakin-2 is a single-pass type I membrane protein that belongs to the uroplakin-2 family. Uroplakin-2 is a component of the asymmetric unit membrane (AUM) and expressed in the ureter, a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. Uroplakin-2 forms heterodimer with UPK1A that is necessary for exiting out of the endoplasmic reticulum (ER) . Uroplakin-2 may play an important role in regulating the assembly of the AUM. AUM is believed to strengthen the urothelium by preventing cell rupture during bladder distention.

NCBI Gene ID

7379

Swiss Prot

O00526

Accession Number

O00526

Tag

C-6 His tag

Type

Recombinant Proteins

Source

Human Cells

Buffer

Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

Shipping Conditions

Room Temp

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=91-723

Calculated Molecular Weight

14.84 kD

Applications Notes

This recombinant protein can be used for biological assays. For research use only.

NCBI Official Name

Uroplakin 2

NCBI Organism

Homo sapiens

Other Product Names

Uroplakin-2, UP2, Uroplakin II, UPII, UPK2

Species

Human

Physical Properties

Lyophilized

CAS Number

9000-83-3

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