CD87 Recombinant Protein
Product Specifications
Background
Urokinase plasminogen activator surface receptor (U-PAR) is also known as PLAUR, Monocyte activation antigen Mo3, CD antigen CD87. PLAUR contains three UPAR/Ly6 domains. U-PAR is expressed in neurons of the rolandic area of the brain (at protein level) and is also expressed in the brain. PLAUR / CD87 interacts with MRC2, SRPX2 and SORL1. PLAUR / UPAR acts as a receptor for urokinase plasminogen activator and plays a role in localizing and promoting plasmin formation. U-PAR mediates the proteolysis-independent signal transduction activation effects of U-PA.
CAS Number
9000-83-3
NCBI Gene ID
5329
Swiss Prot
Q03405
Accession Number
AAH02788
Tag
His Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Cancer, Immunology
Purity
>92% as determined by SDS-PAGE.
Buffer
PBS, pH7.4
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
32.1 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
Plasminogen activator, urokinase receptor
NCBI Organism
Homo sapiens
Background Reference 01
Behrendt N., et al., 2000, J. Biol. Chem. 275:1993-2002.
Background Reference 02
Royer-Zemmour B., et al., 2008, Hum. Mol. Genet. 17:3617-3630.
Background Reference 03
Huai Q., et al., 2006, Science 311:656-659.
Other Product Names
UPAR, PLAUR, CD87, MO3
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized
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