UBE2V2 Recombinant Protein
Product Specifications
Background
Ubiquitin-Conjugating Enzyme E2 Variant 2 (UBE2V2) is an enzyme that belongs to the ubiquitin-conjugating enzyme family. UBE2V2 can be detected in the placenta, colon, liver, and skin. It forms a heterodimer with UBE2N. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains and which leads to protein degradation by the proteasome. UBE2V2 mediates transcriptional activation of target genes. It plays a role in the control of progress through the cell cycle and differentiation. It also plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.
NCBI Gene ID
7336
Swiss Prot
Q15819
Accession Number
Q15819
Tag
N-6 His tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Cancer, Cell Cycle
Buffer
Supplied as a 0.2 um filtered solution of 50mm HEPES,150mM NaCl, pH 7.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=92-156
Calculated Molecular Weight
18.5 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Ubiquitin conjugating enzyme E2 V2
NCBI Organism
Homo sapiens
Other Product Names
Ubiquitin-Conjugating Enzyme E2 Variant 2, DDVit 1, Enterocyte Differentiation-Associated Factor 1, EDAF-1, Enterocyte Differentiation-Promoting Factor 1, EDPF-1, MMS2 Homolog, Vitamin D3-Inducible Protein, UBE2V2, MMS2, UEV2, DDVIT1, EDPF1
Species
Human
Physical Properties
Liquid
CAS Number
9000-83-3
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