UBE2V2 Recombinant Protein

Product Specifications

Background

Ubiquitin-Conjugating Enzyme E2 Variant 2 (UBE2V2) is an enzyme that belongs to the ubiquitin-conjugating enzyme family. UBE2V2 can be detected in the placenta, colon, liver, and skin. It forms a heterodimer with UBE2N. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains and which leads to protein degradation by the proteasome. UBE2V2 mediates transcriptional activation of target genes. It plays a role in the control of progress through the cell cycle and differentiation. It also plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.

CAS Number

9000-83-3

NCBI Gene ID

7336

Swiss Prot

Q15819

Accession Number

Q15819

Tag

N-6 His tag

Type

Recombinant Proteins

Source

E. coli

Field of Research

Cancer, Cell Cycle

Buffer

Supplied as a 0.2 um filtered solution of 50mm HEPES,150mM NaCl, pH 7.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

Shipping Conditions

Dry Ice

Calculated Molecular Weight

18.5 kD

Applications Notes

This recombinant protein can be used for biological assays. For research use only.

NCBI Official Name

Ubiquitin conjugating enzyme E2 V2

NCBI Organism

Homo sapiens

Other Product Names

Ubiquitin-Conjugating Enzyme E2 Variant 2, DDVit 1, Enterocyte Differentiation-Associated Factor 1, EDAF-1, Enterocyte Differentiation-Promoting Factor 1, EDPF-1, MMS2 Homolog, Vitamin D3-Inducible Protein, UBE2V2, MMS2, UEV2, DDVIT1, EDPF1