UBE2S Recombinant Protein
Product Specifications
Background
Ubiquitin-Conjugating Enzyme E2 S (UBE2S) is a member of the Ubiquitin-Conjugating Enzyme family. UBE2S interacts with CDC20, FZR1/CDH1 and VHL. UBE2S can form a thiol ester linkage with Ubiquitin in an Ubiquitin Activating Enzyme-Dependent manner, a characteristic property of Ubiquitin Carrier Proteins. UBE2S acts as an essential factor of the Anaphase Promoting Complex/Cyclosome, a cell cycle-regulated Ubiquitin ligase that controls progression through mitosis. UBE2S is also involved in ubiquitination and subsequent degradation of VHL, resulting in an accumulation of HIF1A.
NCBI Gene ID
27338
Swiss Prot
Q16763
Accession Number
Q16763
Tag
N-GST tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Cancer
Buffer
Supplied as a 0.2 um filtered solution of 50mM HEPES, 150mM NaCl, 2mM DTT, 10% Glycerol, pH 7.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=91-269
Calculated Molecular Weight
50.13 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Ubiquitin conjugating enzyme E2 S
NCBI Organism
Homo sapiens
Other Product Names
Ubiquitin-Conjugating Enzyme E2 S, E2-EPF, Ubiquitin Carrier Protein S, Ubiquitin-Conjugating Enzyme E2-24 kDa, Ubiquitin-Conjugating Enzyme E2-EPF5, Ubiquitin-Protein Ligase S, UBE2S, E2EPF
Species
Human
Protein ID
767928039
Physical Properties
Liquid
CAS Number
9000-83-3
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