UBE2S Recombinant Protein

Product Specifications

Background

Ubiquitin-Conjugating Enzyme E2 S (UBE2S) is a member of the Ubiquitin-Conjugating Enzyme family. UBE2S interacts with CDC20, FZR1/CDH1 and VHL. UBE2S can form a thiol ester linkage with Ubiquitin in an Ubiquitin Activating Enzyme-Dependent manner, a characteristic property of Ubiquitin Carrier Proteins. UBE2S acts as an essential factor of the Anaphase Promoting Complex/Cyclosome, a cell cycle-regulated Ubiquitin ligase that controls progression through mitosis. UBE2S is also involved in ubiquitination and subsequent degradation of VHL, resulting in an accumulation of HIF1A.

CAS Number

9000-83-3

NCBI Gene ID

27338

Swiss Prot

Q16763

Accession Number

Q16763

Tag

N-GST tag

Type

Recombinant Proteins

Source

E. coli

Field of Research

Cancer

Buffer

Supplied as a 0.2 um filtered solution of 50mM HEPES, 150mM NaCl, 2mM DTT, 10% Glycerol, pH 7.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

Shipping Conditions

Dry Ice

Calculated Molecular Weight

50.13 kD

Applications Notes

This recombinant protein can be used for biological assays. For research use only.

NCBI Official Name

Ubiquitin conjugating enzyme E2 S

NCBI Organism

Homo sapiens

Other Product Names

Ubiquitin-Conjugating Enzyme E2 S, E2-EPF, Ubiquitin Carrier Protein S, Ubiquitin-Conjugating Enzyme E2-24 kDa, Ubiquitin-Conjugating Enzyme E2-EPF5, Ubiquitin-Protein Ligase S, UBE2S, E2EPF